Sedative medications (CNS depressants) interacts with L-TRYPTOPHAN
L-tryptophan might cause sleepiness and slowed breathing. Some medications, called sedatives, can also cause sleepiness and slowed breathing. Taking L- tryptophan with sedative medications might cause breathing problems and/or too much sleepiness.
Serotonergic drugs interacts with L-TRYPTOPHAN
L-tryptophan might increase a brain chemical called serotonin. Some medications also have this effect. Taking L-tryptophan along with these medications might increase serotonin too much. This might cause serious side effects including heart problems, seizures, and vomiting.