GAMMA-HYDROXYBUTYRATE (GHB) - Uses, Side Effects, and More

Alcohol (Ethanol) interacts with GAMMA-HYDROXYBUTYRATE (GHB)

Alcohol can cause sleepiness and drowsiness. Taking GHB along with alcohol may greatly increase this effect. Do not take GHB if you have been drinking.

Medications for pain (Narcotic drugs) interacts with GAMMA-HYDROXYBUTYRATE (GHB)

Some medications for pain can cause sleepiness and drowsiness. Taking GHB at the same time may greatly increase this effect. Do not take GHB if you are taking medications for pain. Some medications for pain include meperidine (Demerol), hydrocodone, morphine, OxyContin, and many others.

Medications used to prevent seizures (Anticonvulsants) interacts with GAMMA- HYDROXYBUTYRATE (GHB)

Medications used to prevent seizures can cause sleepiness and drowsiness. Taking GHB at the same time may greatly increase this effect. Also, medications used to prevent seizures may be less effective with GHB because GHB can cause seizures. Do not take GHB if you are taking medications to prevent seizures. Some medications for pain include meperidine (Demerol), hydrocodone, morphine, OxyContin, and many others.

Sedative medications (Benzodiazepines) interacts with GAMMA-HYDROXYBUTYRATE (GHB)

Medications that cause sleepiness and drowsiness are called sedatives. Taking GHB at the same time may greatly increase the effects of sedatives. Do not take GHB if you are taking sedative medications. Some of these sedative medications include clonazepam (Klonopin), diazepam (Valium), lorazepam (Ativan), and others.

Medications used during surgery (Anesthesia) interacts with GAMMA- HYDROXYBUTYRATE (GHB)

Medications used during surgery cause sleepiness and drowsiness. Taking GHB at the same time may greatly increase this effect. Be sure to tell your doctor what natural products you are taking before having surgery. You should stop taking GHB at least two weeks before surgery. Talk to your doctor before stopping sodium oxybate (Xyrem).

Amphetamines interacts with GAMMA-HYDROXYBUTYRATE (GHB)

Amphetamines are drugs that can speed up your nervous system. GHB can slow down your nervous system. Taking GHB along with amphetamines can lead to serious side effects.

Medications for mental conditions (Antipsychotic drugs) interacts with GAMMA- HYDROXYBUTYRATE (GHB)

Medications for mental conditions can cause sleepiness and drowsiness. Taking GHB at the same time may greatly increase this effect. Do not take GHB if you are taking medications for a mental condition. Some of these medications include fluphenazine (Permitil, Prolixin), haloperidol (Haldol), chlorpromazine (Thorazine), prochlorperazine (Compazine), thioridazine (Mellaril), trifluoperazine (Stelazine), and others.

Muscle relaxants interacts with GAMMA-HYDROXYBUTYRATE (GHB)

Muscle relaxants can cause sleepiness and drowsiness. Taking GHB at the same time may greatly increase this effect. Do not take GHB if you are taking muscle relaxants. Some of these muscle relaxants include carisoprodol (Soma), pipecuronium (Arduan), orphenadrine (Banflex, Disipal), cyclobenzaprine, gallamine (Flaxedil), atracurium (Tracrium), pancuronium (Pavulon), succinylcholine (Anectine), and others.

Naloxone (Narcan) interacts with GAMMA-HYDROXYBUTYRATE (GHB)

GHB can affect the brain. Taking naloxone (Narcan) along with GHB might decrease the effects of GHB on the brain.

Ritonavir (Norvir) interacts with GAMMA-HYDROXYBUTYRATE (GHB)

Ritonavir (Norvir) and saquinavir (Fortovase, Invirase) are commonly used together for HIV/AIDS. Taking both of these medications plus GHB might decrease how quickly the body gets rid of GHB. This could cause serious side effects.

Saquinavir (Fortovase, Invirase) interacts with GAMMA-HYDROXYBUTYRATE (GHB)

Saquinavir (Fortovase, Invirase) and ritonavir (Norvir) are commonly used together for HIV/AIDS. Taking both these medications plus GHB might decrease how fast the body gets rid of GHB. This could cause serious side effects.

Sedative medications (CNS depressants) interacts with GAMMA-HYDROXYBUTYRATE (GHB)

Medications that cause sleepiness and drowsiness are called sedatives. Taking GHB at the same times may greatly increase the effects of sedatives. Do not take GHB if you are taking sedative medications. Some sedative medications include clonazepam (Klonopin), lorazepam (Ativan), phenobarbital (Donnatal), zolpidem (Ambien), and others.

Topiramate (Topamax) interacts with GAMMA-HYDROXYBUTYRATE (GHB)

Taking topiramate (Topamax) plus GHB might decrease how quickly the body gets rid of GHB. This could cause serious side effects.

• For excessive daytime sleepiness (narcolepsy): A dose of 25 mg/kg at bedtime, repeated 3 hours later, or a total of with sedative properties.
• For alcohol use disorder: 50 to 150 mg/kg divided into 3 to 6 doses per day. GHB should be used only under close medical supervision.

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