DIMETHYLSULFOXIDE (DMSO) - Uses, Side Effects, and More

Medications applied to the skin, eyes, or ears (Topical drugs) interacts with DIMETHYLSULFOXIDE (DMSO)

DMSO can sometimes increase how much medicine the body absorbs. Applying DMSO along with medications you put on the skin or in the eyes or ears can increase how much medicine your body absorbs. This might increase the effects and side effects of the medicine.

Carboplatin (Paraplatin) interacts with DIMETHYLSULFOXIDE (DMSO)

Using DMSO to dissolve carboplatin (Paraplatin) might reduce how well carboplatin (Paraplatin) works to treat cancer.

Cisplatin (Platinol-AQ) interacts with DIMETHYLSULFOXIDE (DMSO)

Using DMSO to dissolve cisplatin (Platinol-AQ) might reduce how well cisplatin (Platinol-AQ) works to treat cancer.

Oxaliplatin (Eloxatin) interacts with DIMETHYLSULFOXIDE (DMSO)

Using DMSO to dissolve oxaliplatin (Eloxatin) might reduce how well oxaliplatin (Eloxatin) works to treat cancer.

Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with DIMETHYLSULFOXIDE (DMSO)

DMSO might slow blood clotting. Taking DMSO along with medications that also slow clotting might increase the chances of bruising and bleeding. Some medications that slow blood clotting include aspirin, cilostazol (Pletal), clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others.

Sulindac (Clinoril) interacts with DIMETHYLSULFOXIDE (DMSO)

Using DMSO with sulindac might reduce how well sulindac works to treat pain. There is also a concern that using DMSO with sulindac can increase the risk for nerve pain.

Various medications used for glaucoma, Alzheimer disease, and other conditions (Cholinergic drugs) interacts with DIMETHYLSULFOXIDE (DMSO)

DMSO might increase certain chemicals in the brain, heart, and elsewhere in the body. Some medications used for glaucoma, Alzheimer disease, and other conditions also affect these chemicals. Taking DMSO with these medications might increase the chance of side effects. Some of these medications used for glaucoma, Alzheimer disease, and other conditions include pilocarpine (Pilocar and others), donepezil (Aricept), tacrine (Cognex), and others.

Verteporfin (Visudyne) interacts with DIMETHYLSULFOXIDE (DMSO)

Using DMSO with verteporfin might reduce how well verteporfin works.

• For limb pain that usually occurs after an injury (complex regional pain syndrome): Applying a cream containing 50% DMSO to the affected area has been used up to five times daily for 2-12 months.
• For leakage of intravenous (IV) drug from the vein into surrounding skin and tissue (extravasation): A dressing containing 77% to 90% DMSO solution has been applied every 3-8 hours for up to 2 weeks.

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