Water pills (Diuretic drugs) interacts with DIINDOLYLMETHANE
Diindolylmethane can decrease sodium levels. "Water pills" can also decrease sodium levels. Taking "water pills" along with diindolylmethane might make sodium levels drop too low.
Estrogens interacts with DIINDOLYLMETHANE
Diindolylmethane might have effects similar to estrogen. But in some cases, diindolylmethane might oppose the effects of estrogen. Taking large amounts of diindolylmethane might interfere with hormone replacement therapy.
Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates) interacts with DIINDOLYLMETHANE
Some medications are changed and broken down by the liver. Diindolylmethane might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.