BISMUTH - Uses, Side Effects, and More

Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with BISMUTH

Some medications are taken to slow blood clotting. Bismuth salts might increase how quickly blood clots. Taking bismuth salts with these medications might reduce their effects and increase the risk of blood clots. Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.

Aspirin interacts with BISMUTH

Many dietary supplements contain bismuth in the form of bismuth subsalicylate. When taken by mouth, bismuth subsalicylate is broken down into bismuth and salicylate. Because aspirin contains salicylate, taking bismuth with aspirin might increase the effects and side effects of aspirin.

Omeprazole (Prilosec) interacts with BISMUTH

Omeprazole increases how much bismuth the body absorbs. Taking omeprazole with bismuth might increase the effects and side effects of bismuth.

Warfarin (Coumadin) interacts with BISMUTH

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There is some concern that a specific bismuth salt called bismuth subsalicylate might decrease the effects of warfarin. People using warfarin should avoid using bismuth subsalicylate. However, this interaction is not likely for other bismuth salts.

  • For a digestive tract infection that can lead to ulcers (Helicobacter pylori or H. pylori): As a triple therapy, 120 mg bismuth subcitrate, 500 mg amoxicillin, and 250 mg metronidazole four times daily for 14 days have been used. As a bismuth quadruple therapy (BQT), 240-1680 mg of bismuth salts daily, 400-1500 mg of metronidazole daily, 1500-2000 mg of tetracycline daily, and a medication that decreases stomach acid (proton pump inhibitor) for a total of 7 to 14 days have been used. Also as BQT, 480-600 mg of bismuth salts daily, 2000 mg of amoxicillin daily, a proton pump inhibitor, and 100 mg clarithromycin or 1500 mg metronidazole each day for 10-14 days has been used.
  • For stomach ulcers: 700 mg of bismuth subnitrate three times daily for 4 weeks has been used. Also, 300 mg of bismuth subnitrate four times daily, 20 mg of omeprazole twice daily, and 500 mg of amoxicillin four times daily for 2 weeks have been used.
  • For travelers' diarrhea: For prevention, 1.05-2.1 grams of bismuth subsalicylate in two divided doses daily beginning the day before traveling and continuing until 2 days after returning home has been used. As treatment, 525 milligrams of bismuth subsalicylate every 30-60 minutes for a maximum of 8 doses per 24 hours has been used.

CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on ishonest. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. © Therapeutic Research Faculty 2020.

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