COENZYME Q10 - Uses, Side Effects, and More

Medications for cancer (Alkylating agents) interacts with COENZYME Q10

Coenzyme Q10 is an antioxidant. There is some concern that antioxidants might decrease the effectiveness of some medications used for cancers. But it is too soon to know if the interaction occurs. Some medications for cancer include busulfan, carboplatin, cisplatin, cyclophosphamide (Cytoxan), dacarbazine, thiotepa, and many others.

Warfarin (Coumadin) interacts with COENZYME Q10

Warfarin (Coumadin) is used to slow blood clotting while coenzyme Q10 might increase blood clotting. By helping the blood clot, coenzyme Q10 might decrease the effectiveness of warfarin (Coumadin) and increase the risk of dangerous clots. Be sure to have your blood checked regularly. The dose of your warfarin (Coumadin) might need to be changed.

• For coenzyme Q10 deficiency: 150-2400 mg per day.
• For a group of disorders that most often cause muscle weakness (mitochondrial myopathies): 150-160 mg per day, or 2 mg/kg per day. In some cases, doses may be gradually increased to 3000 mg per day.
• For heart failure and fluid build up in the body (congestive heart failure or CHF): 30 mg once daily, or up to 300 mg per day divided into two or three doses for up to 2 years. Also, 2 mg/kg daily for up to one year has been used.
• For nerve pain in people with diabetes (diabetic neuropathy): 400 mg per day for 12 weeks.
• For fibromyalgia: 300 mg daily for about 6 weeks or 200 mg twice daily for 3 months has been used. A combination of 200 mg of coenzyme Q10 (Bio-Quinon Q10, Pharma Nord) plus 200 mg of ginkgo (Bio-Biloba, Pharma Nord) per day for 12 weeks.
• For tissue damage caused when there is limited blood flow and then blood flow is restored (ischemia-reperfusion injury): 150-300 mg per day in up to three divided doses for 1-2 weeks before surgery.
• For preventing migraine: 100 mg three times per day, 150 mg once per day, or 100mg once per day for 3 months. A dose of 1-3 mg/kg per day for 3 months has also been used.
• For multiple sclerosis (MS): 500 mg twice daily for 3 months.
• For a group of inherited disorders that cause muscle weakness and muscle loss (muscular dystrophy): 100 mg per day for 3 months.
• For heart attack: 120 mg per day in two divided doses for up to one year. A combination of 100 mg of coenzyme Q10 (Bio- Quinon, Pharma Nord) and 100 mcg of selenium (Bio-Selenium, Pharma Nord) per day for up to one year has also been used.
• For Peyronie disease: 300 mg per day for 6 months

• For coenzyme Q10 deficiency: 60-250 mg per day in up to three divided doses.
• For preventing migraine: 1-3 mg/kg daily for 3 months has been used in patients aged 3-18 years.
• For a group of inherited disorders that cause muscle weakness and muscle loss (muscular dystrophy): 100 mg daily for 3 months in children aged 8-15 years.

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