What is acne?
Acne is a very common inflammatory condition involving the blockage of pores in the skin (technically pores are called pilosebaceous units).
Acne most commonly occurs during the teenage years and can be very distressing, painful, and embarrassing. Acne frequently starts around 12-14 years of age, and peaks around 16-17 years in females, and 17-19 years in males. Sometimes acne can persist, or even appear for the first time, in adulthood.
There are hundreds of sources of information about managing acne. The following information has been prepared with GPs and dermatologists who treat acne on a daily basis.
What causes acne?
Acne occurs when there is a blockage of a pore by dead skin cells, an increase in natural oil (sebum) in your skin, and the growth of the bacterium called C. acnes (technically called Cutibacterium acnes) formally known as P. acnes (Propionibacterium acnes). If you have acne, all three processes are happening in your skin at one time, causing inflammation around the pore i.e. pimples. The interplay of these factors, which can accompany the natural surge of hormones in adolescence, results in the various acne lesions, commonly known as spots and pimples.
- There is an increase in sebum production, which is controlled by hormones called androgens. When puberty starts there is an increase in the production of androgens that results in an increased production of sebum. This is why acne and adolescence often go hand in hand.
- Skin cells called keratinocytes, that line the wall of the hair follicle are always being shed and replaced with new skin cells. In acne prone skin, there is an overproduction of these cells. This process combined with the over secretion of natural oil may cause the dead skin cells to stick together forming a keratin plug which can cause a blockage in the pore.
- The C. acnes bacteria is present on everyone's skin and usually causes no problems. However, in people prone to acne, the build-up of dead skin, natural oil and the C. acnes bacteria in the pore causes inflammation, recognisable by redness, swelling, heat and pain in the skin surrounding the blocked pore.
- The inflammation and blocked pores lead to the development of acne.
What are the symptoms?
Acne lesions are commonly known as spots and pimples'. They broadly fall into two categories, and the simple terms used below can be useful when describing your symptoms to your doctor or pharmacist: Non-inflammatory lesions
- Blackheads (also called open comedones, are clogged pores that appear as dark bumps on the skin).
- Whiteheads (also called closed comedones, are clogged pores covered by a thin layer of skin that appear as white bumps or spots).
- Papules (small red swollen bumps)
- Pustules (are small red bumps, with a yellow centre filled with pus. They may be painful to touch).
- Nodules (are a firm, red, tender, swollen bump that is hard to the touch and forms under the surface of the skin).
- Cysts (these are large swollen, painful bumps that form deep under the surface of the skin and are filled with pus).
Unfortunately the face is usually the main area affected, but acne can also affect the neck, chest, back and shoulders.
When to contact your GP?
As mentioned above, there are different types of acne (non-inflammatory, inflammatory, others) and your doctor will be able to tell you which type you have. Acne is often graded as mild, moderate, moderate/severe and severe. Even mild cases of acne can cause distress and unhappiness. It is important to visit your GP to receive appropriate advice about treatment, especially before purchasing often-expensive over-the-counter products that may not be suited to your individual symptoms. Visiting a doctor will provide reassurance about how common acne actually is, an impartial opinion about how severe your symptoms are, and what kind of skin care may help you. People frequently think that they will grow out of acne, but unfortunately for some people, it can continue for years and if left untreated may lead to scarring. If you have a diagnosis of acne and would like guidance about an aspect of your care, contact the ISF Helpline here.
How do doctors treat acne?
Choice of treatment depends on the type of lesions and the severity of acne. Treatment aims to reduce acne lesions and prevent scarring.
Acne can be effectively treated and controlled, however, it is important not to become disillusioned if one treatment does not work straignt away. Your doctor may prescribe a number of different treatments before finding one that works best for you. This is usually done in a step-by-step process.
Treatments for acne
Treatments can be divided into 3 main categories
- Topical treatments (creams and ointments) come in the form of washes, gels, lotions and creams that are applied directly to the skin.
- Tablets medications taken by mouth that work throughout the body.
- Other treatments some include, steroid injected into the acne lesion, light and laser devices and chemical peels.
Topical treatments may be used alone or in combination with oral medication. Some preparations are available over-the-counter and others are on prescription. They have various active ingredients and some preparations are combined together to treat acne. They work at reducing inflammation and bacteria and help to unplug blocked pores.
Some of these active ingredients can cause skin irritation; tolerance may be improved by the gradual introduction of treatment. For example, alternate days for the first two weeks and then increase to daily as prescribed and/or according to the product directions. If irritation persists, discuss this with your doctor. The topical treatment should be applied to the whole face and not just the spots. It can take up to 6-8 weeks before you notice an improvement with these topical treatments.
Some of these treatments can cause sun sensitivity, therefore it is important to avoid direct sunlight or use a non-oily (non-comedogenic) broad spectrum sunscreen offering protection from both UVA/UVB, with a minimum SPF 30. Systemic treatments may be prescribed in circumstances where topical treatments have not worked, or are not recommended. These include oral antibiotics and for females the oral contraceptive pill. Other systemic treatment is usually prescribed under specialist supervision due to the potential for side effects, and strict monitoring required while on this medication. Other treatments. In addition to drug therapy, sometimes the doctor may inject corticosteroids directly into acne lesions (intralesional steroid) to help reduce the size and pain of inflamed cysts and nodules.
Laser and light devices are forms of acne treatments that are available in private clinics. These types of treatment have given mixed results and are usually ineffective in severe inflammatory acne. More research is required to evaluate results.
Chemical peels are a form of acne treatment which are available in private clinics. Chemical peels are acids, which come in different strengths, and are applied to the skin. Some of the acids include, glycolic acid (alpha hydroxy acid), salicylic acid (beta hydroxy acid).
12 top tips about acne
These are some of the most important things we think you need to know about acne and how you can best manage it yourself: 1: There is little evidence that food causes acne, a healthy balanced diet is generally advised which includes fresh fruit and vegetables. 2: As mentioned previously, even mild cases of acne can cause distress and unhappiness. If your acne cannot be controlled by over-the-counter acne treatments, go and speak with your GP. 3: Unfortunately patience is necessary; acne responds slowly and a trial period of at least 6 weeks is necessary before any particular therapy is abandoned for another. 4: Use prescribed topical preparations and oral acne medications as directed; e.g. take them at the correct time of day, as often as prescribed, at the right dose and whether antibiotics should be taken with/or without food, as all of these factors can alter the effectiveness of medications.
5: Resist! Resist! Resist! Do not poke, squeeze or pick spots, as this can cause scarring. Do not go pimple popping, this damages your skin!
6: Avoid rubbing and touching spots, this is to decrease the risk of infection.
7: Cleansing When you are on an acne treatment, avoid vigorous washing and scrubbing as this can irritate the skin. Wash the skin with a gentle skin cleanser twice daily, use lukewarm water and pat dry with a clean towel. Completely remove any make-up before going to bed.
8: Shave carefully boys/men who shave, and who have acne, should test both electric and safety razors to see which is more comfortable. Shave gently, slowly and in the direction of the hair growth. Shave only when necessary to reduce the incidence of nicking pimples.
9: Shampoo your hair regularly especially if you have oily hair. If you have long hair, pull your hair back to keep hair out of your face. 10: If applying acne medication to the skin, apply a thin layer to the entire affected area (e.g. all of the face, with clean hands!) and not just to individual spots as this helps treat existing acne and prevent breakouts. 11: Choose cosmetics, toiletries and sunscreens that do not block pores, these products may be labelled non-comedogenic or oil free. In the first few weeks of using acne treatments such as topical retinoid and benzoyl peroxide, it may be difficult to apply foundation evenly because the skin may be red or scaly.
12: Avoid sunburn and suntan many of the medicines used to treat acne can make your skin more sensitive to sunlight. A sunburn that reddens the skin, or suntan that darkens the skin may make the acne less visible and make the skin feel drier. However, these perceived benefits are temporary, and there are known risks of excessive sun exposure, such as premature skin aging and the risk of developing skin cancer.
In some instances, inflammatory acne lesions may form scars as they heal, depending on the individual. During the healing process, loss of collagen, which is often referred to as the body's scaffolding', at the acne lesion site may result in dips in the skin, also known as pitting or ice-pick' scars. Alternatively, there may be an overproduction of collagen, which may result in raised scars also known as keloid scars'.
Severe acne, delay in seeking treatment and relapsing acne are some of the risk factors for scarring. Unfortunately, scarring is irreversible. However, there are treatments available to improve the appearance the scars. Depending on the type of scar, it is best to speak to your GP for onward referral to a qualified specialist who is an expert in providing appropriate treatment.
If there are residual changes in the skin pigmentation, following treatment, skin camouflage may be helpful.
Complementary and alternative treatments
Although you may hear the phrases complementary therapy and alternative therapy used interchangeably, there are important differences between the two.
- A complementary therapy is one that is used along with or alongside conventional (normal or standard) medical treatment for acne (e.g. prescribed topical treatments and systemics). An example of a complementary therapy could be acupuncture. You may choose to talk to your healthcare professional about the pros and cons of these options. Though sometimes expensive, complementary therapies are generally harmless.
- An alternative therapy is one that is used instead of conventional medical treatment. An example could include such things as herbal medicine'.
In accordance with Irish and European law, all conventional medical treatments prescribed by your doctor have to go through careful and thorough scientific testing to prove that they are both safe and effective, but alternative therapies are not held to the same standard. Also, some treatments may interact so it is very important to talk to your doctor before considering using any non- conventional therapies.
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