CBD: it Wont Cure Ailments but it Can Help with Pain, Nausea
Thatâ€™s according to a new study that analyzed years of user comments on Reddit to determine the effectiveness on health and wellness of this active compound found in cannabis plants.
The Qualcomm Instituteâ€™s Center for Data Driven Health at the University of California San Diego reviewed user testimonials and found the majority of them took cannabidiol for diagnosable medical issues, including psychiatric, orthopedic, and sleep conditions, as opposed to using the drug for overall wellness issues.
Their solution was to look at the social media site Reddit and its 430 million users.
The low down on cannabidiol
Cannabidiol sales topped $4.7 billion in the United States in 2019.
However, the only medical use approved by the Food and Drug Administration (FDA) for a cannabis-derived drug product is for epilepsy, said Dr. Lenny Cohen, a Chicago-based neurologist.
Cohen noted that some cannabis derivatives are approved for nausea in people being treated for cancer.
â€œThis is where official approval ends,â€ Cohen told ishonest. â€œThe rest are pure speculation and anecdotal references. One of the biggest pushes for cannabinoids happened due to the overuse of narcotics with the unfounded belief that cannabinoids can be as beneficial and less addictive than narcotics.â€
Cohen said the physiology just doesnâ€™t match up, although CBD does possess properties that can keep someone calm.
â€œIn my personal practice, unfortunately, I did not see equivalent results for pain coverage for those who had been on narcotics previously,â€ he said. â€œThat being said, cannabinoids might be beneficial for narcotics-naÃ¯ve patients. There are a number of studies on use of cannabinoids for neuropathic pain, for example. Unfortunately, many of them are flawed.â€
Why the study was done
Caleb Chen runs The Highest Critic, a website reviewing cannabis products.
Heâ€™s also a Reddit moderator who told ishonest he can shed light on demographic caveats present in a study based on Reddit.
â€œThey classified the self-reported medical conditions as symptoms, but itâ€™s impossible to know from an internet comment whether the reported medical condition has been formally diagnosed, or even would be presented to a certified medical doctor,â€ Chen said.
â€œThe study admits this as a flaw and even notes that some symptoms could bely undiagnosed medical conditions,â€ he added.
â€œI think the study did a good job with the data that was available â€” and there really isnâ€™t much. I also think they had a foregone conclusion going into the study,â€ he said.
Changing views on CBD
Dr. Bill Code specializes in anesthesia and has used cannabis to treat people with chronic pain and seizures.
He told ishonest that CBD â€œis a potent anti-inflammatory and so can help many problems in controlling pain and inflammationâ€ without the side effects of other drugs.
While Code said there hasnâ€™t been enough research done, he doesnâ€™t believe the Reddit study was an accurate gauge. He said understanding of CBD changed during the sample period.
â€œThe article critiqued that there were not enough medical conditions specifically named,â€ Code said. â€œThe FDA and medical societies hugely discourage this, so I suspect this has a great influence. Prior to 2018â€“2019, when Epidiolex (containing CBD for epilepsy) was approved, hemp oil containing CBD was seen more as a dietary supplement. This initiated many of the wellness statements or posts, as these are less provocative with the FDA than medical conditions.â€
â€œI agree with the article in that changes should be legislated, and accurate lab evaluation and subsequent accurate labeling would greatly assist both the consumer and the medical people. Then we can compare apples to apples,â€ he said.
Using CBD for pain, nausea
Carey Clark, PhD, RN, the chair of the medical cannabis program at Pacific College of Health and Science in San Diego, told ishonest the National Academies of Science, Engineering, and Medicine in 2017 detailed evidence around cannabis and various states of disease and illness.
â€œWe do know that cannabinoids like CBD are effective for managing pain, muscle spasms associated with multiple sclerosis, and chemotherapy-induced nausea and vomiting. Many other illnesses have moderate or low levels of evidence of their effectiveness,â€ said Clark.
â€œHowever, there is a lot of ongoing research, and we know anecdotally that patients say cannabinoids help them feel better,â€ Clark said.
â€œI am concerned that people have access to safe, tested, and high-quality cannabinoids,â€ she added.
â€œCannabis is the most researched plant on the planet, with over 30,000 studies available. It has been used for thousands of years. What we need now are better studies,â€ she said.
Dr. Craig K. Svensson is a professor of medicinal chemistry and molecular pharmacology at Purdue University in Indiana.
He told ishonest the study is useful for â€œinsight into the real-world use of CBD, as it informs researchers the various reasons for which people are consuming CBD, as well as how that may be changing over time.â€
He said there are two big issues.
â€œThe first, apart from seizures, [is] might CBD be useful for the treatment of conditions like pain, anxiety, and related disorders? More research is need to give enough data to make these conclusions,â€ Svensson said.
â€œThe second issue is quality of products,â€ he added.
Aside from prescription drugs such as Epidolex, CBD products arenâ€™t required to undergo FDA approval. Svensson noted that label inaccuracies are a concern.
â€œThe bottom line is there is only one disease for which there is sufficient evidence that CBD is effective for a medical condition. That is two rare forms of seizure disorder, and less than half of patients with those disorders benefit from CBD,â€ he said.
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